Selected Publications

2024

Flick, H*., Venbakkam, A*., Singh, P.k., Layish, B., Huang, S., Radhakrishnan, R., kvaratskelia, m., Engelman, A.N., Kane, M.

Interplay between the cyclophilin homology domain of RANBP2 and MX2 regulates HIV-1 capsid dependencies on nucleoporins

BioRxiv. doi.org/10.1101/2024.08.12.607676 *these authors contributed equally

LAyish, B., Goli, R., Flick, H., Huang, S., Zhang, R.Z., kvaratskelia, m., Kane, M.

Virus specificity and nucleoporin requirements for MX2 activity are affected by GTPase function and capsid-CypA interactions

PLoS Pathogens. doi.org/10.1371/journal.ppat.1011830

2023

Zhang, R.Z., Mele, V., Robben, L., Kane, M.

Genetic differences between 129S substrains affect antiretroviral immune responses.

Journal of Virology. doi.org/10.1128/jvi.01930-22

2020

Kane, M*., Mele, V., Liberatore, R., Bieniasz, P.D*.

Inhibition of spumavirus gene expression by PHF11.

PLoS Pathogens. doi.org/10.1371/journal.ppat.1008644 *corresponding author

2018

Kane, M., Rebensburg, S., Takata, M., Zang, T.M., Yamashita, M., Kvaratskhelia, M., Bieniasz, P.D.

Nuclear pore heterogeneity affects HIV-1 infection and the antiviral activity of Mx2.

eLife. doi: 10.7554/eLife.35378.001


Kane, M*., Deiss, F., Chervonsky, A.V., Golovkina, T.

A single locus controls interferon gamma-independent antiretroviral neutralizing antibody responses.

Journal of Virology. doi: 10.1128/JVI.00725-18 *corresponding author

2017

Denzin, L.K., Khan, A.A., Virdis, F., Wilks, J., Kane, M., Beilinson, H., Dikiy, S., Case, L.K., Roopenian, D., Witkowski, M., Chervonsky, A.V., Golovkina, T.

Neutralizing antibody responses to viral infections are linked to the non-classical MHC Class II gene H2-Ob.

Immunity. doi: 10.1016/j.immuni.2017.07.013

2016

Kane, M*., Zang, T.M*., Rihn, S.J*., Zhang, F., Kueck, T., Alim, M., Schoggins, J., Rice, C.M., Wilson, S.J., Bieniasz, P.D.

Identification of interferon-stimulated genes with antiretroviral activity.

Cell Host & Microbe. doi: 10.1016/j.chom.2016.08.005 *these authors contributed equally

2014

Busnadiego, I., Kane, M., Rihn, S., Preugschas, H., Hughes, J., Blanco-Melo, D., Strouvelle, V., Zang, T., Willett, B., Boutell, C., Bieniasz, P.D., and Wilson, S.J.

Host and viral determinants of Mx2 antiretroviral activity.

Journal of Virology. doi:10.1128-JVI.00214-14

2013

Kane, M., Yadav, S.S., Bitzegeio, J., Kutluay, S.B., Zang, T., Wilson, S.J., Schoggins, J.W., Rice, C.M., Yamashita, M., Hatziooannou, T., Bieniasz, P.D.

MX2 is an interferon-induced inhibitor of HIV-1 infection.

Nature. doi:10.1038/nature12653

Preview: Haller, O. Dynamins are forever: MxB inhibits HIV-1. Cell Host and Microbe

2011

Kane, M., Case, L.K., Kopaskie, K., Kozlova, A., MacDearmid, C., Chervonsky, A.V., Golovkina, T.V.

Successful virus transmission depends on microbiota.

Science. doi:10.1126/science.1210718

News & Analysis: Pennisi, E. Gut Bacteria Lend a Molecular Hand to Viruses. Science

Research Highlight: David, R. The gut microbiota: friend or foe? Nature Reviews Microbiology


Kane, M., Case, L.K., Wang, C., Yurkovetskiy, L., Dikiy, S., Golovkina T.V.

Innate immune sensing of retroviral infection via Toll-like receptor 7 occurs upon viral entry.

Immunity. doi:10.1016/j.immuni.2011.05.011

Preview: Liberatore, R. and Bieniasz, P. Sensing Retroviruses. Immunity


Kane, M., Case, L.K., Golovkina T.V.

Vital role for CD8+ cells in controlling retroviral infections.

Journal of Virology. doi:10.1128/JVI.01768-10

2007

Velez MG, Kane, M., Liu S, Gauld SB, Cambier JC, Torres RM, Pelanda R.

Ig allotypic inclusion does not prevent B cell development or response.

Journal of Immunology. doi:10.4049/jimmunol.179.2.1049


Reviews

Kane, M. and Golovkina T.V.

Mapping viral susceptibility loci in mice. 2019

Annual Review of Virology. doi.org/10.1146/annurev-virology-092818-015544

Kane, M. and Golovkina T.V.

Realities of virus sensing. 2012

Microbes and Infection. doi:10.1016/j.micinf/2012.06.006

Kane, M. and Golovkina T.V.

Common threads in persistent viral infections. 2010

Journal of Virology. doi:10.1128/JVI.01905-09